SeasonBite

  • Recipes
    • Easy Dinners
    • One-Pot Meals
    • Seafood
  • Contact
  • About
menu icon
go to homepage
  • Recipes
    • Easy Dinners
    • One-Pot Meals
    • Seafood
  • Contact
  • About
search icon
Homepage link
  • Recipes
    • Easy Dinners
    • One-Pot Meals
    • Seafood
  • Contact
  • About
×

Irresistibly Cheesy Stuffed Manicotti with Meat Sauce Delight

Published: Jan 12, 2026 by Sierra Lane · This post may contain affiliate links · Leave a Comment

Jump to Recipe Print Recipe

There I was, staring at my pantry, wondering how to turn a simple night into a cozy culinary escape. That’s when I remembered my beloved Stuffed Manicotti with Meat Sauce recipe. This dish is a shining star of homemade comfort food, effortlessly combining savory flavors with a delightful pasta hug. With minimal prep time and a crowd-pleasing flair, it transforms any dinner into a cherished gathering. The velvety meat sauce paired with creamy cheese-filled manicotti brings joy to both the cook and those lucky enough to share the meal. Ready to roll up your sleeves and create a dish that will have everyone reaching for seconds? Let’s dive in!

Stuffed Manicotti with Meat Sauce

Why is this recipe a must-try?

Comforting and satisfying, this Stuffed Manicotti with Meat Sauce brings home the essence of Italian cuisine. Flavor-packed meat sauce envelops creamy cheese-stuffed pasta, creating a dish that’s truly irresistible. Quick prep time means you can enjoy deliciousness without hours in the kitchen. Plus, it’s a crowd-pleaser, making it perfect for family dinners or gatherings. If you're a fan of hearty meals, check out more of our comfort food recipes to keep the flavors coming.

Stuffed Manicotti with Meat Sauce Ingredients

For the Manicotti
• Manicotti pasta tubes – these sturdy shells are perfect for holding in all that cheesy goodness!
• 1 ½ cups ricotta cheese – provides a creamy texture that balances the meatiness of the sauce.
• 1 cup mozzarella cheese – melt-in-your-mouth ooey-gooey cheese that adds an irresistible stretch.
• ½ cup grated Parmesan cheese – for that extra layer of flavor that elevates each bite.
• 1 large egg – binds the filling together for a seamless stuffing experience.
• Salt and pepper – season to taste for a well-rounded flavor profile.

For the Meat Sauce
• 1 pound ground beef – the heart of your meat sauce, bringing hearty richness.
• 1 medium onion, chopped – adds sweetness and depth to your sauce.
• 2 cloves garlic, minced – enhances the overall flavor and gives warmth to the dish.
• 28 ounces crushed tomatoes – the base of your sauce, providing moisture and richness.
• 2 teaspoons Italian seasoning – a blend that infuses your sauce with traditional Italian flavors.
• Salt and pepper – season to your liking for a perfectly balanced sauce.

This Stuffed Manicotti with Meat Sauce is a dish that embraces comfort, flavor, and togetherness. Get ready to impress your family and friends with this delightful creation!

Step‑by‑Step Instructions for Stuffed Manicotti with Meat Sauce

Step 1: Preheat the Oven
Start by preheating your oven to 375°F (190°C). This ensures that your Stuffed Manicotti with Meat Sauce cooks evenly. While the oven is warming up, gather your baking dish and cooking equipment. A 9x13-inch dish works wonderfully for this recipe, so have it ready on your countertop.

Step 2: Prepare the Meat Sauce
In a large skillet over medium heat, cook 1 pound of ground beef, breaking it apart with a spatula. Sauté it until browned, about 6-8 minutes. Add chopped onion and minced garlic, cooking until the onion is translucent. Stir in 28 ounces of crushed tomatoes and 2 teaspoons of Italian seasoning, simmering for 10-15 minutes. The sauce should thicken and smell amazing!

Step 3: Cook the Manicotti
While the sauce simmers, bring a pot of salted water to a boil. Carefully add the manicotti pasta tubes and cook for about 6-8 minutes until al dente. Drain the pasta and gently rinse under cold water to stop the cooking process. Set aside to cool slightly before filling these delicious pasta shells with the cheesy mixture.

Step 4: Make the Cheese Filling
In a mixing bowl, combine 1 ½ cups of ricotta cheese, 1 cup of mozzarella cheese, ½ cup of grated Parmesan cheese, 1 large egg, salt, and pepper. Mix until the ingredients are fully blended and the filling is creamy. This delightful mixture will perfectly complement the savory meat sauce in your Stuffed Manicotti.

Step 5: Stuff the Manicotti
Using a spoon or a piping bag, carefully fill each manicotti tube with the cheese mixture. Don't overstuff, as the filling will expand during baking. Once all the shells are filled, arrange them neatly in the prepared baking dish. This step is crucial to ensure every bite is packed with flavor.

Step 6: Assemble the Dish
Spread half of the meat sauce evenly over the bottom of the baking dish. Place the stuffed manicotti on top, then pour the remaining meat sauce over the filled tubes. This allows the flavors to meld beautifully while keeping the pasta moist during baking. You’ll love the sight of this comforting dish!

Step 7: Bake the Manicotti
Cover the baking dish with aluminum foil, ensuring it doesn’t touch the cheese. Bake in the preheated oven for 25 minutes. After that, remove the foil and bake for an additional 10-15 minutes, or until bubbling and golden. When the cheese is melted and slightly crispy on top, your Stuffed Manicotti with Meat Sauce is ready to be devoured.

Stuffed Manicotti with Meat Sauce

Stuffed Manicotti with Meat Sauce Variations

Feel free to sprinkle your own culinary magic onto this gorgeous stuffed manicotti masterpiece!

  • Vegetarian Delight: Replace ground beef with sautéed mushrooms, zucchini, and spinach for a wholesome twist. This variation adds earthy flavors while keeping it satisfying.
  • Spicy Kick: Add red pepper flakes to the meat sauce for a delightful heat that wakes up your taste buds. Just a pinch can transform your dish into a fiery favorite.
  • Cheesy Explosion: Mix in additional types of cheese, like provolone or fontina, for an even gooier filling. Imagine the rich, melty goodness that awaits with each forkful!
  • Gluten-Free: Substitute manicotti pasta with gluten-free varieties made from rice or lentils. Enjoy the classic flavors without compromising dietary needs!
  • Herb-Infused: Wake up the flavors by incorporating fresh herbs like basil or oregano into the cheese filling. The fresh taste will elevate the dish and bring it alive.
  • Creamy Spin: Blend ricotta with a bit of cream cheese for an ultra-creamy interior. The velvety texture will take every bite over the top – truly luscious!
  • Mexican Flair: Mix taco seasoning into the meat sauce and use pepper jack cheese in the filling. This twist creates a fun fusion everyone will love.
  • Baked with Veggies: Layer some sautéed bell peppers and onions between the pasta layers for added texture and nutrients. It’s a flavorful way to sneak in more veggies!

Embrace your inner chef and customize this recipe to suit your family's palate or your adventurous spirit! Have fun experimenting, and don’t hesitate to revisit our delightful comfort food recipes for more inspiration.

How to Store and Freeze Stuffed Manicotti with Meat Sauce

Fridge: Store leftover Stuffed Manicotti in an airtight container for up to 3 days, ensuring the pasta stays moist and flavorful.

Freezer: For longer storage, freeze uncooked stuffed manicotti in a single layer on a baking sheet. Once frozen, transfer them to a freezer-safe bag for up to 3 months.

Reheating: To reheat, thaw overnight in the fridge, then bake at 350°F (175°C) covered for about 30 minutes until heated through, ensuring the flavors from the meat sauce shine.

Serving Tip: For the best taste, add a sprinkle of fresh cheese on top before reheating to revive that cheesy goodness in your Stuffed Manicotti!

What to Serve with Stuffed Manicotti with Meat Sauce

A warm, inviting meal awaits when you find the perfect side dishes to complement your pasta delight.

  • Crusty Garlic Bread: This golden, buttery bread, infused with garlic, creates a delightful contrast to the rich meat sauce. Perfect for soaking up those delicious flavors!

  • Caesar Salad: Crisp romaine lettuce, crunchy croutons, and zesty dressing add a refreshing crunch that balances the heaviness of the manicotti. The bright flavors will elevate your dining experience.

  • Roasted Vegetables: Seasoned veggies like zucchini, bell peppers, and carrots bring vibrant color and a wholesome touch to the table. Their natural sweetness pairs beautifully with savory pasta dishes.

  • Creamy Mashed Potatoes: Fluffy, buttery mashed potatoes provide an extra comforting side that complements the richness of the meat sauce. Plus, they offer a cozy texture contrast to the al dente pasta.

  • Bruschetta: Topped with fresh tomatoes, basil, and olive oil, these crunchy bites offer a burst of freshness that cuts through the hearty flavors of the meal. It’s like a little taste of Italy on a plate!

  • Italian Red Wine: A glass of Chianti or Sangiovese beautifully enhances the flavors of the meat sauce and the cheeses. This pairing creates a dining experience that feels sophisticated yet relaxed.

  • Tiramisu: End your meal on a sweet note with this classic Italian dessert. The fluffy layers of mascarpone and espresso combined with cocoa bring a satisfying finish after the savory main course.

Creating a well-rounded meal with these delicious pairings will leave everyone at your table cheering for seconds!

Expert Tips for Stuffed Manicotti with Meat Sauce

  • Pasta Cooking Time: Ensure you don’t overcook the manicotti; it should be al dente. Overcooked pasta will fall apart when filling.

  • Easy Filling: Use a piping bag for stuffing the manicotti for less mess and a more controlled fill. This ensures every tube is properly filled and tastes delicious.

  • Layering Flavors: Always spread half the meat sauce in the baking dish before placing the stuffed manicotti. This keeps the pasta moist and prevents it from drying out.

  • Resting Time: Let the dish sit for about 5 minutes after baking. This allows the flavors to meld and makes serving easier.

  • Garnish Thoughtfully: A sprinkle of fresh basil or parsley before serving adds color and a fresh flavor pop, making your Stuffed Manicotti with Meat Sauce even more appealing!

Make Ahead Options

These Stuffed Manicotti with Meat Sauce are perfect for busy weeknights and can be prepped ahead to save you time! You can prepare the entire dish and refrigerate it up to 24 hours before baking. Simply assemble everything up until the baking step, cover tightly with foil, and store it in the fridge to maintain freshness. If needed, you can also make the meat sauce and cheese filling separately, storing them in the refrigerator for up to 3 days. When you're ready to enjoy, just add the sauce over the stuffed manicotti and bake as instructed, allowing for a delightful homemade meal that tastes just as delicious as if it were made fresh!

Stuffed Manicotti with Meat Sauce

Stuffed Manicotti with Meat Sauce Recipe FAQs

How do I choose the best manicotti pasta?
To ensure your Stuffed Manicotti turns out fabulously, look for manicotti shells that are firm and without cracks. A fresh pack will provide the best texture. If you see any broken pieces in the package, consider a different brand or opt for a new box to guarantee that every bite is delightful.

What’s the best way to store leftover Stuffed Manicotti?
Absolutely! Store leftover Stuffed Manicotti in an airtight container in the refrigerator for up to 3 days. You can also place it in individual portions in meal prep containers for convenience. Just be sure to cover it to keep the pasta moist and prevent it from drying out!

Can I freeze Stuffed Manicotti, and how?
Yes! To freeze your uncooked Stuffed Manicotti with Meat Sauce, spread the filled tubes on a baking sheet, ensuring they don't touch, and freeze until solid (about 1-2 hours). Then, transfer them to a freezer-safe bag, removing as much air as possible. They can be frozen for up to 3 months! When ready to enjoy, thaw overnight in the fridge before baking.

What should I do if my manicotti shells break while filling?
No problem at all! If you have a broken manicotti shell, simply use it as a makeshift “pasta layer” at the bottom of your dish. You can also patch the broken shell with a bit more cheese filling during assembly. It adds character to the dish, celebrating the beauty of homemade cooking!

Are there any dietary considerations for this recipe?
Very! If you’re looking to make this recipe gluten-free, consider using gluten-free manicotti pasta, reducing wheat exposure without sacrificing flavor. For dairy-free options, you could swap the cheeses for plant-based alternatives. Always double-check ingredient labels to avoid any hidden allergens.

How can I enhance the flavor of my meat sauce?
For an extra burst of flavor in your meat sauce, consider adding a splash of red wine during the simmering stage. This not only deepens the sauce but adds a sophisticated touch too! If you enjoy spicy dishes, a pinch of red pepper flakes can enhance the flavor and bring a delightful kick to every bite.

Stuffed Manicotti with Meat Sauce

Irresistibly Cheesy Stuffed Manicotti with Meat Sauce Delight

This Stuffed Manicotti with Meat Sauce is a comforting Italian dish that combines savory flavors with a creamy cheese filling.
Print Recipe Pin Recipe
Prep Time 30 minutes mins
Cook Time 45 minutes mins
Resting Time 5 minutes mins
Total Time 1 hour hr 20 minutes mins
Course Easy Dinners
Cuisine Italian
Servings 6 servings
Calories 500 kcal

Equipment

  • 9×13-inch baking dish
  • large skillet
  • mixing bowl
  • Pot
  • spatula
  • Piping bag

Ingredients
  

For the Manicotti

  • 12 tubes Manicotti pasta these sturdy shells are perfect for holding in all that cheesy goodness!
  • 1.5 cups ricotta cheese provides a creamy texture
  • 1 cup mozzarella cheese adds an irresistible stretch
  • 0.5 cup grated Parmesan cheese for added flavor
  • 1 large egg binds the filling together
  • Salt season to taste
  • Pepper season to taste

For the Meat Sauce

  • 1 pound ground beef the heart of the meat sauce
  • 1 medium onion chopped
  • 2 cloves garlic minced
  • 28 ounces crushed tomatoes the base of the sauce
  • 2 teaspoons Italian seasoning infuses the sauce with traditional flavors
  • Salt season to taste
  • Pepper season to taste

Instructions
 

Step-by-Step Instructions

  • Preheat your oven to 375°F (190°C).
  • In a large skillet over medium heat, cook the ground beef for 6-8 minutes.
  • Add chopped onion and minced garlic; cook until onion is translucent.
  • Stir in crushed tomatoes and Italian seasoning; simmer for 10-15 minutes.
  • Bring a pot of salted water to a boil and cook manicotti for 6-8 minutes until al dente.
  • In a mixing bowl, combine the cheeses, egg, salt, and pepper; mix until creamy.
  • Fill each manicotti tube with the cheese mixture.
  • Spread half of the meat sauce in a baking dish; place stuffed manicotti on top.
  • Pour remaining meat sauce over the stuffed manicotti.
  • Cover with foil and bake for 25 minutes; remove foil and bake for another 10-15 minutes.

Notes

Garnish with fresh basil or parsley before serving for added flavor and appeal.

Nutrition

Serving: 1servingCalories: 500kcalCarbohydrates: 35gProtein: 30gFat: 25gSaturated Fat: 12gPolyunsaturated Fat: 3gMonounsaturated Fat: 7gTrans Fat: 1gCholesterol: 95mgSodium: 800mgPotassium: 600mgFiber: 4gSugar: 6gVitamin A: 500IUVitamin C: 5mgCalcium: 300mgIron: 3mg
Keyword Cheesy, comfort food, Homemade, meat sauce, pasta, Stuffed Manicotti with Meat Sauce
Tried this recipe?Let us know how it was!

More Easy Dinners

  • Caribbean-Style Plantain Curry
    Delicious Caribbean-Style Plantain Curry Ready in 40 Minutes
  • Tinga de Pollo
    Delicious Tinga de Pollo: A Flavorful Homemade Delight
  • Spinach Stuffed Pie
    Savory Spinach Stuffed Pie for a Cozy Homemade Feast
  • Maggiano's Lasagna
    Mouthwatering Maggiano's Lasagna You Can Make at Home

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Recipe Rating




About Sierra Lane

Season-obsessed cook sharing quick, produce-packed recipes for everyday meals—straight from my farmers’ market basket to your table.

Sierra’s Story

Popular

  • Butter Pecan Cake Loaf with Cream Cheese Icing
    Delicious Butter Pecan Cake Loaf with Cream Cheese Icing Recipe
  • Coffee And Walnut Loaf
    Irresistible Coffee And Walnut Loaf for Cozy Afternoons
  • Cottage Cheese Peanut Butter Smoothie
    Creamy Cottage Cheese Peanut Butter Smoothie Bliss
  • Strawberry Topped Cheesecake
    Delicious Strawberry Topped Cheesecake to Impress Friends

Seasonal

  • Honey-Glazed Shallots with Crispy Bacon
    Sweet and Savory Honey-Glazed Shallots with Crispy Bacon Delight
  • Strawberry Topped Cheesecake Dessert
    Decadent Strawberry Topped Cheesecake Dessert to Savor
  • Cheesy Pepperoni Pizza Bombs
    Irresistibly Cheesy Pepperoni Pizza Bombs for Easy Snacking
  • Keto Pecan Square
    Irresistibly Delicious Keto Pecan Square Recipe to Savor

Footer

Copyright © 2025 SeasonBite Privacy Policy Terms & Conditions Disclaimer