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Savory Juicy Baked Cheeseburger Meatloaf You'll Crave

Published: Feb 5, 2026 by Sierra Lane · This post may contain affiliate links · Leave a Comment

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Just the other day, I caught myself reminiscing about family dinners filled with laughter and the savory scent of comfort meals wafting through the kitchen. That's when I decided it was high time to whip up a dish that combines nostalgia with a modern twist: Savory Juicy Baked Cheeseburger Meatloaf. This recipe not only brings the beloved flavors of a cheeseburger to the dinner table, but it also boasts an impressive crowd-pleasing profile that makes it perfect for any home-cooked occasion. With a prep time of only 15 minutes, and the added benefit of being freezer-friendly, it's a go-to for busy weeknights. Ready to dive into a deliciously hearty meal that’s sure to make your family’s taste buds dance? Let’s get started!

Savory Juicy Baked Cheeseburger Meatloaf

Why is this meatloaf a must-try?

Comforting, nostalgic flavors: This Savory Juicy Baked Cheeseburger Meatloaf captures the essence of a classic cheeseburger in a fun new form.

Effortless preparation: With just 15 minutes of prep, you’ll have a delicious meal in no time—perfect for busy weeknights.

Crowd-pleasing appeal: Kids and adults alike will love digging into this hearty dish, making it a sure hit at family dinners.

Melt-in-your-mouth cheesiness: The layer of cheddar cheese adds a gooey richness that takes this meatloaf over the top.

Plus, for those looking to explore more creative takes on comfort food, be sure to check out our Chicken and Dumplings recipe or our mouthwatering Stuffed Bell Peppers to keep the flavor adventure going!

Savory Juicy Baked Cheeseburger Meatloaf Ingredients

• Here’s everything you need to create this masterpiece!

For the Meatloaf

  • 1 pound ground beef – Choose lean beef for a perfect balance of flavor and moisture.
  • 1 whole egg – Acts as a binder to keep the meatloaf together.
  • ½ cup breadcrumbs – Helps absorb moisture and gives the meatloaf a nice texture.
  • ¼ cup milk – Keeps the meatloaf juicy; consider using any milk you have on hand.
  • ¼ cup onion, finely chopped – Adds a hint of sweetness and depth to the flavor.
  • 1 tablespoon ketchup – Enhances flavor while also adding moisture.
  • 1 teaspoon Worcestershire sauce – Elevates the savory profile of the meat.
  • 1 teaspoon Dijon mustard – Adds a subtle tang that complements the cheeseburger flavor.
  • ½ teaspoon garlic powder – Infuses an aromatic kick that's essential in savory dishes.
  • ½ teaspoon salt – Essential for bringing out all the flavors in the meatloaf.
  • ¼ teaspoon black pepper – A touch of heat that balances the dish nicely.

For the Cheese Layer

  • 4 ounces cheddar cheese, sliced – Melts beautifully, creating a gooey surprise in every bite.

For the Topping

  • 2 tablespoons ketchup – Adds a sweet-tangy glaze that completes your Savory Juicy Baked Cheeseburger Meatloaf.

Step‑by‑Step Instructions for Savory Juicy Baked Cheeseburger Meatloaf

Step 1: Preheat and Prepare
Begin by preheating your oven to 350°F (175°C). While the oven heats up, lightly grease a loaf pan with cooking spray or a drizzle of oil to ensure your Savory Juicy Baked Cheeseburger Meatloaf comes out easily after baking.

Step 2: Combine Mixture
In a large mixing bowl, combine 1 pound of ground beef, 1 whole egg, ½ cup breadcrumbs, ¼ cup milk, ¼ cup finely chopped onion, 1 tablespoon ketchup, 1 teaspoon Worcestershire sauce, 1 teaspoon Dijon mustard, ½ teaspoon garlic powder, ½ teaspoon salt, and ¼ teaspoon black pepper. Gently mix until just combined, being careful not to overwork the meat, to keep it tender.

Step 3: Form the Base
Scoop half of the meat mixture into the greased loaf pan. Use your hands to press it down gently, creating an even layer that fills the bottom of the pan. This forms the base for your cheesy filling, ensuring every bite will have that delicious cheeseburger essence.

Step 4: Add the Cheese Layer
Layer 4 ounces of sliced cheddar cheese over the pressed meat mixture in the loaf pan. Ensure to leave a small border around the edges so that the cheese doesn’t spill over while baking, creating a delicious gooey surprise in the center of your Savory Juicy Baked Cheeseburger Meatloaf.

Step 5: Seal the Meatloaf
Carefully top the cheese layer with the remaining half of the meat mixture. Gently press down to seal the edges, making sure the cheese is completely enclosed within the meat; this step ensures the delicious flavors meld together as it cooks.

Step 6: Apply the Topping
Spread 2 tablespoons of ketchup evenly over the top of the meatloaf. This not only adds a touch of sweetness but also creates a beautiful glaze that complements the savory flavors of your Savory Juicy Baked Cheeseburger Meatloaf as it bakes.

Step 7: Bake to Perfection
Place the loaf pan in the preheated oven and bake for 45 to 50 minutes. Keep an eye on the time, and check for doneness by inserting an instant-read thermometer into the center, which should read 160°F for perfectly cooked meatloaf.

Step 8: Rest and Slice
Once the meatloaf is fully cooked, remove it from the oven and let it rest for 10 minutes. This step is crucial, as it allows the juices to redistribute, making it easier to slice and ensuring each piece of your Savory Juicy Baked Cheeseburger Meatloaf is moist and flavorful.

Savory Juicy Baked Cheeseburger Meatloaf

How to Store and Freeze Savory Juicy Baked Cheeseburger Meatloaf

Fridge: Store any leftovers in an airtight container for up to 3 days. Make sure it’s cooled completely before sealing to maintain texture.

Freezer: Wrap slices tightly in plastic wrap or aluminum foil, then place in a freezer-safe bag. It will stay fresh for up to 3 months.

Reheating: For best results, thaw overnight in the fridge before reheating. Warm in the oven at 350°F for about 20 minutes, or until heated through, ensuring your Savory Juicy Baked Cheeseburger Meatloaf remains deliciously moist.

Savory Juicy Baked Cheeseburger Meatloaf Variations

Feel free to get creative and personalize this meatloaf to suit your taste preferences and dietary needs!

  • Turkey Option: Substitute ground turkey for a lighter, yet delicious alternative. It offers a milder flavor that's perfect for those watching their red meat intake.

  • Vegetarian Delight: Replace ground beef with lentils or a mix of finely chopped mushrooms and walnut. This gives a hearty texture and keeps the savoriness intact.

  • Cheese Choices: Experiment with different cheeses like mozzarella or pepper jack for a gooey, flavorful twist. Each cheese brings its unique flavor profile, transforming the dish altogether.

  • Spice it Up: Add a teaspoon of cayenne pepper or chopped jalapeños for an extra kick! Spice lovers will appreciate the delicious heat mingling with the savory meat.

  • Herb Infusion: Mix in chopped fresh herbs like parsley or basil for a burst of freshness. This brightens the flavors and adds a lovely aroma to each slice of meatloaf.

  • BBQ Twist: Swap the ketchup topping for your favorite barbecue sauce for a smoky, sweet finish. This is perfect for outdoor grilling vibes, even in the winter months!

  • Bonus Layering: Consider layering sautéed bell peppers and onions into the meat mixture for additional flavor and texture. This creates a delightful surprise and enhances the overall dish.

  • Gluten-Free Version: Use gluten-free breadcrumbs or cooked quinoa as a binder to make this meatloaf suitable for gluten-sensitive friends and family. You'll love the results just as much!

For more family-friendly meal ideas, don’t forget to check out our delicious Chicken and Dumplings or the colorful and nutritious Stuffed Bell Peppers!

Make Ahead Options

These Savory Juicy Baked Cheeseburger Meatloaf options are perfect for busy home cooks looking to save time! You can prepare the entire meatloaf mixture up to 24 hours in advance. Simply combine all the ingredients as directed, shape it into the loaf, and cover it tightly with plastic wrap before refrigerating. This keeps the meatloaf fresh and ensures the flavors meld together beautifully. When you’re ready to bake, just pop it in the oven straight from the fridge, adding an extra 5-10 minutes to the cooking time to ensure it heats through completely. This way, you’ll be enjoying a comforting, homemade meal with minimal effort on a busy weeknight!

Expert Tips for Savory Juicy Baked Cheeseburger Meatloaf

  • Mix Gently: To avoid a dense meatloaf, mix your ingredients just until combined. Overworking the meat can lead to toughness.

  • Cheese Placement: Ensure your cheese is placed in the center with a border of meat around it. This prevents the cheese from leaking out while baking.

  • Check Doneness: Always use an instant-read thermometer; the internal temperature should reach 160°F. Undercooking can lead to food safety issues, while overcooking dries out your meatloaf.

  • Let It Rest: Waiting 10 minutes before slicing is essential. This resting time allows juices to redistribute for a moist, flavorful Savory Juicy Baked Cheeseburger Meatloaf.

  • Customize Spices: Feel free to adjust the spices or add your favorite herbs to enhance the flavors according to your preference!

What to Serve with Savory Juicy Baked Cheeseburger Meatloaf

Imagine gathering around the table, the hearty scent of your delicious meatloaf filling the air, beckoning family and friends to dive into a comforting, satisfying meal.

  • Garlic Mashed Potatoes: Creamy, buttery, and fluffy, they soak up the savory juices perfectly, creating a delightful contrast to the meatloaf. This classic pairing transforms every bite into pure comfort.

  • Classic Caesar Salad: Crisp romaine with tangy dressing adds freshness and crunch, balancing the richness of the meatloaf. The anchovies in the dressing bring a delightful umami surprise.

  • Sweet Corn on the Cob: A side of tender, sweet corn adds a burst of summer flavor and sweetness, enhancing the savory profile of your dish. Plus, who can resist the joy of corn sliding off the cob?

  • Roasted Brussels Sprouts: A touch of caramelization brings out their earthy flavors, making them a deliciously nutty complement to the cheeseburger meatloaf. The crispy edges make for a delightful textural contrast.

  • Homemade Coleslaw: The refreshing crunch of slaw serves as a perfect palate cleanser and adds a delightful crunch. The tangy dressing cuts through the richness of the meatloaf, leaving you asking for more.

  • Red Wine: A glass of medium-bodied red wine, like Merlot or Cabernet Sauvignon, pairs beautifully, enhancing the savory flavors of the meatloaf and complementing the richness of the cheddar cheese.

  • Chocolate Chip Cookies: For dessert, warm, gooey chocolate chip cookies make for a nostalgic ending. Their sweetness perfectly balances the hearty meal, reminding everyone of home.

Savory Juicy Baked Cheeseburger Meatloaf

Savory Juicy Baked Cheeseburger Meatloaf Recipe FAQs

How do I select the best ground beef for this recipe?
Absolutely! Look for 80/20 ground beef for the ideal balance of fat and lean meat. This ensures your Savory Juicy Baked Cheeseburger Meatloaf stays juicy and flavorful. If you prefer a healthier version, leaner cuts like 90/10 can also work, but you might need to add a tad more moisture with a splash of milk or an additional egg.

What’s the best way to store leftovers?
Very! Store your leftover meatloaf in an airtight container in the fridge for up to 3 days. Make sure it cools to room temperature before sealing, as this helps maintain its texture. When ready to enjoy, a simple reheating in the oven will get it ready to savor again!

Can I freeze Savory Juicy Baked Cheeseburger Meatloaf?
Absolutely, freezing is a great option! To freeze, wrap slices tightly in plastic wrap or aluminum foil, then transfer them to a freezer-safe bag. This keeps your meatloaf fresh for up to 3 months. When you’re ready to eat, thaw it overnight in the fridge, then reheat in the oven at 350°F for about 20 minutes to enjoy its delightful flavors again.

What do I do if my meatloaf is too dry?
If you find your meatloaf turns out dry, it’s often because it was overcooked. An instant-read thermometer should read 160°F in the center for the perfect doneness. If it’s already done, consider serving it with a homemade sauce or gravy, which can help add moisture and flavor to each slice.

Can I make this meatloaf gluten-free?
Of course! Simply substitute breadcrumbs with gluten-free options such as crushed gluten-free crackers, oats, or even ground almonds for a nutritious twist. Ensure that other ingredients like sauces are also gluten-free to maintain this delicious dish in a way you can safely enjoy.

Is this meatloaf pet-friendly?
While the Savory Juicy Baked Cheeseburger Meatloaf is safe for pets in small amounts, it's best to avoid sharing it with them regularly due to certain ingredients like onions, which can be harmful to dogs. Always consult with your vet if unsure about specific ingredients!

Savory Juicy Baked Cheeseburger Meatloaf

Savory Juicy Baked Cheeseburger Meatloaf You'll Crave

A delicious take on comfort food, this Savory Juicy Baked Cheeseburger Meatloaf combines nostalgic flavors with a modern twist, perfect for family dinners.
Print Recipe Pin Recipe
Prep Time 15 minutes mins
Cook Time 50 minutes mins
Resting Time 10 minutes mins
Total Time 1 hour hr 15 minutes mins
Course Easy Dinners
Cuisine American
Servings 4 slices
Calories 320 kcal

Equipment

  • Loaf pan
  • mixing bowl
  • Oven

Ingredients
  

For the Meatloaf

  • 1 pound ground beef Choose lean beef for a perfect balance of flavor and moisture.
  • 1 whole egg Acts as a binder.
  • ½ cup breadcrumbs Helps absorb moisture.
  • ¼ cup milk Keeps the meatloaf juicy.
  • ¼ cup onion, finely chopped Adds sweetness and depth.
  • 1 tablespoon ketchup Enhances flavor and adds moisture.
  • 1 teaspoon Worcestershire sauce Elevates the savory profile.
  • 1 teaspoon Dijon mustard Adds a subtle tang.
  • ½ teaspoon garlic powder Infuses an aromatic kick.
  • ½ teaspoon salt Brings out the flavors.
  • ¼ teaspoon black pepper Balances the dish.

For the Cheese Layer

  • 4 ounces cheddar cheese, sliced Melts beautifully.

For the Topping

  • 2 tablespoons ketchup Adds a sweet-tangy glaze.

Instructions
 

Step-by-Step Instructions

  • Preheat your oven to 350°F (175°C) and grease a loaf pan.
  • In a large mixing bowl, combine all meatloaf ingredients and mix gently.
  • Scoop half of the meat mixture into the loaf pan and press to form the base.
  • Layer the sliced cheddar cheese over the pressed meat mixture.
  • Top with the remaining meat mixture and seal edges.
  • Spread ketchup evenly over the top of the meatloaf.
  • Bake in the preheated oven for 45 to 50 minutes.
  • Let the meatloaf rest for 10 minutes before slicing.

Notes

Mix gently to avoid a dense meatloaf, and let it rest before slicing for better texture.

Nutrition

Serving: 1sliceCalories: 320kcalCarbohydrates: 18gProtein: 25gFat: 18gSaturated Fat: 7gPolyunsaturated Fat: 1gMonounsaturated Fat: 9gCholesterol: 85mgSodium: 650mgPotassium: 400mgFiber: 1gSugar: 3gVitamin A: 300IUVitamin C: 1mgCalcium: 150mgIron: 3mg
Keyword comfort food, family dinner, Freezer-Friendly Meal, Hearty Dish, meatloaf recipe, Savory Juicy Baked Cheeseburger Meatloaf
Tried this recipe?Let us know how it was!

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About Sierra Lane

Season-obsessed cook sharing quick, produce-packed recipes for everyday meals—straight from my farmers’ market basket to your table.

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